{"id":2066,"date":"2017-05-17T10:17:25","date_gmt":"2017-05-17T01:17:25","guid":{"rendered":"https:\/\/www.tsukuba-sci.com\/?p=2066"},"modified":"2017-05-17T10:17:25","modified_gmt":"2017-05-17T01:17:25","slug":"%e3%83%8b%e3%83%af%e3%83%88%e3%83%aa%e3%81%aeips%e7%b4%b0%e8%83%9e%e3%81%ae%e5%8a%b9%e7%8e%87%e7%9a%84%e3%81%aa%e6%a8%b9%e7%ab%8b%e3%81%ab%e6%88%90%e5%8a%9f","status":"publish","type":"post","link":"https:\/\/www.tsukuba-sci.com\/?p=2066","title":{"rendered":"\u30cb\u30ef\u30c8\u30ea\u306eiPS\u7d30\u80de\u306e\u52b9\u7387\u7684\u306a\u6a39\u7acb\u306b\u6210\u529f"},"content":{"rendered":"

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\u3000\u9ce5\u985e\u306e<\/span>iPS<\/span><\/span>\u7d30\u80de\u306e\u6a39\u7acb\u306b\u3064\u3044\u3066\u306f\u6d77\u5916\u3067\u6570\u4f8b\u5831\u544a\u304c\u3042\u308b\u304c\u3001\u52b9\u679c\u7684\u306a\u6a39\u7acb\u6cd5\u306f\u672a\u78ba\u7acb\u3067\u3042\u3063\u305f\u3002\u4eca\u5f8c\u3001\u8a66\u9a13\u7ba1\u5185\u3067\u9ce5\u985e\u306e\u69d8\u3005\u306a\u7d30\u80de\u3092\u5275\u308a\u51fa\u305b\u308b\u3088\u3046\u306b\u306a\u308b\u305f\u3081\u3001\u611f\u67d3\u75c7\u3084\u8fb2\u85ac\u306a\u3069\u304c\u7d76\u6ec5\u5371\u60e7\u9ce5\u985e\u306e\u751f\u614b\u306b\u4e0e\u3048\u3066\u3044\u308b\u5f71\u97ff\u306a\u3069\u3092\u52b9\u7387\u7684\u306b\u8a55\u4fa1\u3067\u304d\u308b\u3068\u3044\u3046\u3002<\/span><\/p>\n

\u3000\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u4eca\u56de\u3001\u5b9f\u9a13\u30e2\u30c7\u30eb\u306b\u30cb\u30ef\u30c8\u30ea\u306e\u30d2\u30ca\u306e\u4f53\u7d30\u80de\u3092\u7528\u3044\u3001\u3053\u306e\u7d30\u80de\u306b\u591a\u80fd\u6027\u3092\u6301\u305f\u305b\u308b\u305f\u3081\u306e\u521d\u671f\u5316\u8a98\u5c0e\u907a\u4f1d\u5b50\u3068\u3057\u3066<\/span>Oct3\/4<\/span><\/span>\u3092\u306f\u3058\u3081\u3068\u3059\u308b<\/span>6<\/span><\/span>\u7a2e\u985e\u306e\u907a\u4f1d\u5b50\u3092\u5c0e\u5165\u3057\u305f\u3002\u305d\u306e\u969b\u3001<\/span>MyoD<\/span><\/span>\u3068\u3044\u3046\u907a\u4f1d\u5b50\u306e\u8ee2\u5199\u6d3b\u6027\u9818\u57df\u306e\u4e00\u90e8\u3092<\/span>Oct3\/4<\/span><\/span>\u907a\u4f1d\u5b50\u306b\u7d50\u5408\u3057\u3066\u3001<\/span>Oct3\/4<\/span><\/span>\u306e\u8ee2\u5199\u6d3b\u6027\u3092\u7279\u306b\u9ad8\u3081\u308b\u5de5\u592b\u3092\u3057\u305f\u3002<\/span><\/p>\n

\u3000\u3053\u306e\u8ee2\u5199\u6d3b\u6027\u578b<\/span>Oct3\/4<\/span><\/span>\u306a\u3069\uff16\u3064\u306e\u907a\u4f1d\u5b50\u3092\u3001\u907a\u4f1d\u5b50\u306e\u904b\u3073\u5c4b\u3067\u3042\u308b\u30d9\u30af\u30bf\u30fc\u306b\u9023\u7d50\u3057\u3001\u5916\u6765\u907a\u4f1d\u5b50\u3092\u76ee\u7684\u7d30\u80de\u306e<\/span>DNA<\/span><\/span>\u306b\u5c0e\u5165\u3059\u308b\u30b7\u30b9\u30c6\u30e0\u3067\u3042\u308b<\/span>PiggyBac<\/span><\/span>\u30c8\u30e9\u30f3\u30b9\u30dd\u30be\u30f3\u30b7\u30b9\u30c6\u30e0\u3092\u7528\u3044\u3066\u4f53\u7d30\u80de\u306b\u5165\u308c\u305f\u3002<\/span><\/p>\n

\u3000\u305d\u306e\u5f8c\u306e\u89b3\u5bdf\u3067\u3001\u30cb\u30ef\u30c8\u30ea\u306e\u4f53\u7d30\u80de\u306e\u521d\u671f\u5316\u304c\u8a8d\u3081\u3089\u308c\u305f\u3002\u307e\u305f\u3001\u3053\u306e\u521d\u671f\u5316\u7d30\u80de\u306f\u9577\u6642\u9593\u306e\u7d99\u4ee3\u304c\u53ef\u80fd\u3067\u3042\u3063\u305f\u3002\u3053\u306e\u7d30\u80de\u306e\u5206\u5316\u80fd\u529b\u3092\u8abf\u3079\u305f\u3068\u3053\u308d\u3001\u5185\u80da\u8449\u3001\u4e2d\u80da\u8449\u3001\u5916\u80da\u8449\u306e\u4e09\u80da\u8449\u306b\u5206\u5316\u3057\u3001\u591a\u80fd\u6027\u3092\u6709\u3059\u308b<\/span>iPS<\/span><\/span>\u7d30\u80de\u3067\u3042\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002<\/span><\/p>\n

\u3000\u3053\u306e<\/span>iPS<\/span><\/span>\u7d30\u80de\u306e\u591a\u80fd\u6027\u72b6\u614b\u3092\u3055\u3089\u306b\u8a73\u3057\u304f\u89e3\u6790\u3057\u305f\u3068\u3053\u308d\u3001\u6a39\u7acb\u3057\u305f<\/span>iPS<\/span><\/span>\u7d30\u80de\u306f<\/span>FGF<\/span><\/span>\u3068\u3044\u3046\u5897\u6b96\u56e0\u5b50\u3068\u3001<\/span>PouV<\/span><\/span>\u304a\u3088\u3073<\/span>Nanog<\/span><\/span>\u3068\u3044\u3046\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u306b\u3088\u308a\u591a\u80fd\u6027\u304c\u7dad\u6301\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u3068\u3044\u3046\u3002<\/span><\/p>\n

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